“For centuries, humanity has sought to unravel the mysteries of ageing. What causes our bodies to change and decline over time? Is it a pre-programmed process or simply the result of wear and tear? Recent breakthroughs in the field of ageing clocks have shed new light on these age-old questions, and a study published in the journal Nature Aging may have brought us one step closer to understanding the very nature of ageing itself.
Imagine that your body is like a complex machine, with countless gears and mechanisms working together to keep you functioning. As you age, this machine begins to break down – but what if there was a way to measure and predict these changes? Enter the concept of ageing clocks.
Ageing clocks are essentially biological indicators that can provide a measure of an individual’s “biological age” – that is, how old their body seems rather than the number of years they’ve been alive (chronological age). These clocks are built using various types of biological data, such as DNA methylation patterns or gene expression levels. By tracking changes in these markers over time, scientists can create models that predict an individual’s biological age with remarkable accuracy.
So, what causes these changes in the first place? One theory is that ageing is a pre-programmed process, like a ticking clock that counts down to our eventual demise”.
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Epigenetics 🧬
Unlike the outdated and conventional method of measuring age with time, epigenetic ageing also known as biological age can be accelerated and reversed.
Epigenetic ageing and DNA methylation 🧬 has been argued to be related to all mortality in later life, however, it is thought not to be a cause of ageing but a marker that can be used to judge accelerated ageing.
By utilising this important marker, it may be possible to predict many diseases 🏥 and lifestyle conditions before they come to pass. With the fundamental aim of decelerating the ageing process and preventing these ailments from occurring in the first place.
Chronological age Vs Biological age.
The vast majority of us will be completely unaware that we actually have two ages:
Chronological age refers the exact number of years you have been alive and as predictable as night follows day, your date of birth and age cannot be altered.
While biological age is a true reflection of how your cells are ageing and how they have been affected by exogenous and endogenous stressors such as your diet 🥗, exercise 🏋🏼, lifestyle, and environment 🌎, which will affect your epigenetics.
To date there are 2992 scientific publications on biological age and epigenetics, so it is very well characterised.
Muhdo Health understands that we all come with a set of unique genetic predispositions, but our lifestyle & environments will affect those same genetic traits 🧬, and either dilute or accentuated them through Epigenetics.