𝐁𝐮𝐭 𝐰𝐡𝐲?
Well, the vast majority of us are now light deprived during the day as we work indoors more, and dark deprived during the night, as we have our house 💡 💡lights, TV 📺, laptops 💻and phones 📱on late into the evening.
What does this unnatural blue light 💡 💡in the evening mean to our health?
No Melatonin!!
Melatonin, otherwise known as the “Sleep Hormone” 😴has so many more specific and crucial effects within your body than just helping us to fall asleep.
We are only now beginning to understand why it is so important and why getting a good night sleep 😴is by far the most important element of your longevity routine.
Melatonin is thought to activate and regulate over 500 genes 🧬that are involved in DNA 🧬repair and antioxidant function within your body.
We have seen everyone jumping on the bandwagon about sulforaphane 🥬 activating something called Nrf2. Well, Melatonin might have more of a beneficial effect!!
Melatonin has a potent antioxidant effect by up regulating endogenous cellular antioxidant defence enzymes such as SOD, GPX1 and CAT (in the same way that broccoli and 🥬sulforaphane does), by activating the Nrf2 -ARE transcription pathway, which helps protect cells from oxidative stress and inflammation. 🔥
In addition, Melatonin induces Phase II Detox enzymes, GCLM, NQO1 and HO-1 to name but a few.
We (Muhdo Health) have also seen that taking a dose of 5mg/day increased SOD, CAT, and glutathione reductase activities and reduced malondialdehyde (MDA) levels, which is a carcinogenic compound causing potential toxic ☠️🤮effects.
It is also crucial that we obtain sufficient selenium levels as GPX1 (Glutathione Peroxidase) is a seleno-protein structure. And how much GPX1 you produce will largely come down to the amount of selenium you are consuming and is within your system.